A home-built refraction-based optical recording system for pharmacological investigations

The Ecophysiological and Environmental Toxicological Research Group and Environmental Toxicological Research Group of the Balaton Limnological Research Institute, in collaboration with researchers at the University of Sussex (UK), developed a novel and unique in vitro pharmacological method based on a refraction-based optical recording approach and contractile tissue preparations. The recording system has an own Java application named DigiRec, which was developed by Mr. Tamás Barta (bartatamas@gmail.com) and runs under Linux. The system was tested and validated on isolated heart preparations obtained from the well-established molluscan model species, the great pond snail (Lymnaea stagnalis). The developed system can be a suitable tool both in neuroscience and ecotoxicology.