+  Ágnes Vehovszky - Senior Research Fellow


Ágnes Vehovszky CSc.
senior research fellow
Institute Building C, room 104
tel: +36 87 448 244 ext №206
fax: +36 87 448 006
vehovszky.agnesemail_cim

CV
Research area
Research description
Selected publications
Collaborations
Major projects
Society Memberships
Teaching


  CV
Time and place of birth:

 
1954, Budapest, Hungary

Graduation, MSc:

1978, Msc Eövös Loránd University, Budapest, Hungary

PhD:

1983, Eötvös Loránd University, Budapest, Hungary; "Synaptic inputs of the identified bimodal pacemaker neuron in the snail Helix pomatia L."

CSc:

1995, Hungarian Academy of Sciences, Budapest; Hungary "False transmitters as tools for identification of serotonin-containing neurons and their synaptic connections in snail (Helix) central nervous system."

Recent position:

senior research fellow


  Research Area

Invertebrate neurobiology, neurotoxicology, environmental toxikology; characterization of neurotoxic effects on aquatic invertebrate animals.


  Research Description

Toxic effects are described as alterations in neuronal activity controlling different forms of behavioural patterns, moreover, the neuromodulatory effects are analysed on a sigle neuronal level, as changes of neuronal communication and membrane functions. Finally, identification of the neuronal targets (membrane receptors, ion channels, etc.) and background mechanisms concerned using combination sof electrophysiological, morphological and pharmacological, as well as molecular techniques.


  Selected Publications

Vehovszky, A., Elliott, C.J.H. (2001): Activation and reconfiguration of fictive feeding by the octopamine-containing modulatory OC interneurons in the pond snail Lymnaea stagnalis J. Neurophysiol., 86: 792-808.

Ágnes Vehovszky, Henriette Szabó and Christopher Elliott (2005): Octopamine increases the excitability of neurons in the snail feeding system by modulation of inward sodium current but not outward potassium currents. /BMC Neuroscience, 6:70.

Ágnes Vehovszky, Henriette Szabo, Laszlo Hiripi, Christopher J. H. Elliott, Laszlo Hernadi (2007): Behavioural and neural deficits induced by rotenone in the pond snail Lymnaea stagnalis. A possible model for Parkinson's disease in an invertebrate. European J. Neurosci., 25, 2123 – 2130.

Á. Vehovszky, H. Szabó, A. Ács, J. Gyori, A. Farkas: (2010): Effects of rotenone and other mitochondrial complex I inhibitors on the brine shrimp Artemia. Acta Biol. Hung., 61, 4, 401-410.

Otilia Antal, Mariann Karisztl-Gacsi, Anna Farkas, Attila Kovács, András Ács, Norbert Töro, Gyula Kiss, Martin L. Saker, János Gyori, Gáspár Bánfalvi, Ágnes Vehovszky (2011) Screening the toxic potential of Cylindrospermopsis raciborskii strains isolated from Lake Balaton, Hungary. Toxicon, 57, 831-840.

Ágnes Vehovszky, A. W. Kovács, Henriette Szabó, J. Gyori, Anna Farkas (2012): Neurotoxic effects evoked by cyanobacterial extracts suggest multiple receptors involved in electrophysiological responses of molluscan (CNS, heart) models. Acta Biol. Hung., 63. Suppl. 2. 160-170.


  Collaborations

Robert Walker - University of Southampton, School of Biological Sciences, UK

Christopher Elliott - University of York, Department of Biology, York, UK


  Major Projects

2001 - 2004
"Octopamine in a rhythmic network: cellular mechanisms of heterosynaptic modulation". Initiative Collaboration Research Grant supported by the Wellcome Trust. (collaboration with Dr. Christopher Elliott, University of York, Department Biology, UK).

2002 - 2005
"The possible role of serotonin and dopamine in the regulation of gastropod feeding". supported by the Hungarian Academy Sciences, OTKA grant (project manager Dr. László Hernádi)

2006 - 2009
"Neuronal substrate(s) of cyanotoxin effects produced by freshwater algae - in vivo and in vitro studies on model freshwater invertebrate organisms". supported by the Hungarian Academy Sciences OTKA grant (project manager: Dr. Vehovszky Ágnes)


  Society Memberships

1993 -
Hungarian Neuroscience Association (MITT).

1989 -
International Society of Invertebrate Neurobiology (ISIN).

2003 - 2011
International Society of Invertebrate Neurobiology (ISIN) secretary.

2008 -
Society of Hungarian Toxicologists.

2011 -
Invertebrate Neuroscience, editorial board member.


  Teaching

2011 -
Summer training for undergraduates in behavioral biology, neurotoxicology "Neurotoxicology" summer course for MSc students